Publicaciones Recientes

Jefe de Grupo: Cristina Sánchez

Blasco-Benito, S., Seijo-Vila, M., Caro-Villalobos, M., Tundidor, I., Andradas, C., García-Taboada, E., Wade, J., Smith, S., Guzmán, M., Pérez-Gómez, E., Gordon, M., Sánchez, C (2018). Appraising the “entourage effect”: Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer. Biochemical Pharmacology 2952: 30238-7.

Guzmán, M., Sánchez, C.,  G. Velasco, G. (2017) Potencial antitumoral de los cannabinoides. Efectos terapéuticos de los cannabinoides (ISBN: 978-84-697-2394-4).

Sánchez, C. (2017) Preparaciones de cannabis utilizadas con fines terapéuticos. Efectos terapéuticos de los cannabinoides (ISBN: 978-84-697-2394-4).

Alkatout, I., Hübner, F., Wenners, A., Hedderich, J., Wiedermann, M., Sánchez, C., Röcken, C., Mathiak, M., Maass, N., Klapper, W. (2017) In situ localization of tumor cells associated with the epithelial-mesenchymal transition marker Snail and the prognostic impact of lymphocytes in the tumor microenvironment in invasive ductal breast cancer. Experimental and Molecular Pathology 102:268-275.

Díaz-Alonso, J., de Salas-Quiroga, A., Paraíso-Luna, J., García-Rincón, D., Garcez, P., Parsons, M., Andradas, C.  Sánchez, C., Guillemot, F., Guzmán, M., Galve-Roperh, I. (2016) Loss of cannabinoid CB1 receptors induces cortical migration malformations and increases seizure susceptibility. Cerebral Cortex (doi: 10.1093/cercor/bhw309).

Andradas, C., Blasco-Benito, S., Castillo-LLuva, S., Dillenburg-Pilla, P., Diez-Alarcia, R., Juanes-García, A., García-Taboada, E., Hernando-Llorente, R., Soriano, J., Hammann, S., Wenners, A., Alkatout, I., Klapper, W., Rocken, C., Bauer, M., Arnold, N., Quintanilla, M., Megías, D., Vicente-Manzanares, M., Urigüen, L., Gutkind, J.S., Guzmán, M., Pérez-Gómez, E.,  Sánchez, C. (2016) Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer. Oncotarget 7:47565-47575.

Velasco, G., Sánchez, C., Guzmán, M. (2016)  Anticancer mechanisms of cannabinoids. Current Oncology 23:S23-S32.

Marín-Ramos, N., Alonso, D.,  Ortega-Gutierrez, S., Ortega-Nogales, F., Balabasquer, M., Vazquez-Villa, H., Andradas, C.  Blasco-Benito, S., Pérez-Gómez, E., Canales, A., Jimenez-Barbero, J., Marquina, A., Moscoso del Prado, J., Sánchez, C., Martín-Fontecha, M., López-Rodrí­guez, M. (2015) New inhibitors of angiogenesis with antitumor activity in vivo. Journal of Medicinal Chemistry 58:3757-66.

Tomé-Amat, J., Olombrada, M., Ruiz-de-la-Herrán, J., Pérez-Gómez, E., Andradas, C.  Sánchez, C., Martínez, L., Martínez-del-Pozo, Á., Gavilanes, J.G.,  Lacadena., J. (2015) Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin alpha-sarcin in nude mice bearing human colorectal cancer xenografts. SpringerPlus 4:168.

Morales, P., Blasco-Benito, S., Andradas, C., Gómez-Cañas, M., Flores, J.M., Goya, P., Fernández-Ruiz, J.J., Sánchez, C., Jagerovic N., (2015) Selective, non-toxic CB2 cannabinoid o-quinone with in vivo activity against triple negative breast cancer. Journal of Medicinal Chemistry 58:2256-64.

Pérez-Gómez, E., Andradas, C., Blasco-Benito, S., Caffarel, M.M., García-Taboada, E., Villa-Morales, M., Moreno, E., Hamann, S., Martín-Villar, E., Flores, J.M., Wenners, A., Alkatout, I., Klapper, W., Röcken, C, Bronsert, P., Stickeler, E., Staebler, A., Bauer, M., Arnold, N., Soriano, J., Pérez-Martínez, M., Megías, D., Moreno-Bueno, G., Ortega-Gutiérrez, S., Artola, M., Vázquez-Villa, H., Quintanilla, M., Fernández-Piqueras, J., Canela, E.I., McCormick, P.J, Guzmán M., Sánchez, C. (2015) Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer. Journal of the National Cancer Institute 107:djv077.

Salazar, M., Lorente, M., García-Taboada, E., Pérez-Gómez, E., Dávila, D., Zúñiga-García, P., Flores, J.M., Rodríguez, A., Hegedus, Z., Mosén-Ansorena, D., Aransay, A., Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J., Dusetti, N., Guzmán, M., Francis, S., Carracedo, A., Kiss-Toth, E., Velasco G. (2015) TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling. Mol Cell Oncol 18:e980134.

Velasco, G., Sánchez, C., Guzmán, M. (2015) Endocannabinoids and cancer. Endocannabinoids. Handbook of Experimental Pharmacology (ISBN: 978-3-319-20825-1).

Velasco, G., Sánchez, C., Guzmán, M., (2014) Some potential therapeutic targets for phytocannabinoids: Cancer. Handbook of Cannabis (ISBN: 978-0-19-966268-5).

Salazar, M., Lorente, M.,  García-Taboada, E., Pérez-Gómez, E., Dávila, D., Zúñiga-García, P., Flores, J.M., A. Rodríguez, Hegedus, Z., Mosén-Ansorena, D., Aransay, A.  Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J., Dusetti, N., Guzmán, M., Francis, S., Carracedo, A., Kiss-Toth, E., Velasco, G. (2015) Loss of Tribbles pseudokinase-3 promotes AKT-driven tumorigenesis via FOXO inactivation. Cell Death and Differentiation 22:131-144.

Moreno, E., Andradas, C., Medrano, M., Caffarel, M.M., Pérez-Gómez, E., Blasco-Benito, S., Gómez-Cañas, M., Pazos, M.R., Irving, A.J., Lluís, C., Canela, E.I., Fernández-Ruiz, J.J., Guzmán, M., McCormick, P.J., Sánchez, C. (2014) Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling. The Journal of Biological Chemistry 289:21960-72.

Pérez-Gómez, E., Andradas, C., Flores, J.M., Quintanilla, M., Paramio, J.M., Guzmán, M., Sánchez, C. (2013) The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas. Oncogene 32:2534-2542.

Andradas, C., Caffarel, M.M., Pérez-Gómez, E., Guzmán, M., Sánchez, C., (2013) The role of GPR55 in cancer. Endocannabinoids: actions at non-CB1/CB2 cannabinoid receptors (ISBN: 978-1-4614-4668-2) (eBook: 978-1-4614-4669-9).

Caffarel, M.M., Andradas, C., Pérez-Gómez, E., Guzmán, M., Sánchez, C. (2012) Cannabinoids: a new hope for breast cancer therapy? Cancer Treatment Reviews 38:911-918.

Velasco, G., Sánchez, C., Guzmán, M., (2012) Towards the use of cannabinoids as antitumour agents. Nature Reviews Cancer 12:436-44.