Cristina graduated in Biology at Universidad Complutense de Madrid in 1994. She started her scientific career as an undergraduate student at the laboratory of Dr. Ramos and Dr. Fernández-Ruiz (School of Medicine, Complutense University), where she first took contact with the field of cannabinoid research. Once graduated, she moved to Dr. Guzmán’s laboratory (School of Biology, Complutense University), where she studied the effect of cannabinoids on lipid and carbohydrate intermediate metabolism first and on cancer cell proliferation later. She obtained her PhD with Honors in Biochemistry and Molecular Biology at Universidad Complutense de Madrid in 2000. During her postdoc at Dr. Piomelli’s laboratory (University of California Irvine, 2000-2003) she studied the involvement of another group of bioactive lipids (lysophosphatidic acid and related compounds) on pain initiation. In 2004, Cristina returned to Spain with a “Ramón y Cajal” contract (aimed at repatriating Spanish researchers from abroad) and she started coordinating a new line of research within Dr. Guzmán’s laboratory. In particular, the goal of her research is to understand and exploit cannabinoids as potential antitumoral agents in breast cancer. More recently, she has also focused her attention on new cannabinoid receptors and their possible involvement in cannabinoid antitumoral action in breast cancer and other type of tumors.
Eduardo graduated in Biochemistry at Universidad Autónoma de Madrid in 2002. He obtained his PhD (Extraordinary Prize) from the Biomedical Research Institute (IIBM), Biology of Cancer department in 2007. During his PhD work, he investigated the role of endoglin, a TGFbeta co-receptor, as a suppressor of malignancy during carcinogenesis. He joined our lab in October 2009. He is now focused on the study of cannabinoid receptors and breast cancer using, as a major tool, mouse models. In 2020 he became a Titular Professor, position that he currently holds.
Isabel graduated in Health Biology at Universidad de Alcalá (Spain) in 2015. Later that year, she enrolled the MSc in Molecular Biomedicine from the Autonomous University of Madrid (Spain). For her MSc Thesis, she moved to the German Cancer Research Center (DKFZ) in Heidelberg, where she studied the role of the tumor suppressor gene NF1 in tumor migration. In 2016, she joined our lab thanks to a PFIS predoctoral contract from the Carlos III Health Institute. She is now working on her PhD project, aimed at exploring how the endocannabinoid system can be related to the mammary gland development and to the onset and progression of breast tumors.
Marta graduated in Biology at Universidad de Vigo in 2016. Then, in the academic course 2016-2017 she did her Master’s Degree in Biochemistry, Molecular Biology and Biomedicine at the Complutense University of Madrid. During this period, she joined our group to perform her Master’s Thesis. Currently, she is studying Cannabis sativa whole-plant extracts as better therapeutic tools than pure cannabinoids in preclinical models of breast cancer with a PhD grant from Hospital 12 de Octubre.