Publicaciones Recientes

Jefe de Grupo: Guillermo Velasco

López-Valero, I., Sáiz-Ladera, C., Torres, S., Hernández-Tiedra, S., García-Taboada, E., Rodríguez-Fornés, F., Barba, M., de León, D.D., Salvador-Tormo, N., Guzmán, M., Sepúlveda, J.M., Sánchez, P., Lorente, M., Velasco, G. (2018). Targeting Glioma Initiating Cells With A Combined Therapy Of Cannabinoids And Temozolomide. Biochemical Pharmacology.

Hernández-Tiedra, S., Fabrias, G., Dávila, D., Salanueva, I., Casas, J., Montes, R.,  Antón, Z., García-Taboada, E., Salazar-Roa, M., Lorente, M., Nylandsted, J., Armstrong, J., López- Valero, I., McKee, C., Serrano-Puebla, A., García-López, R., González-Martínez, J., Abad, J.,  Hanada, K., Boya, P., Goñi, F., Guzmán, M., Lovat, P.,  Jaattela, M., Alonso, A., Velasco, G. (2016) Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy 11, 2213-2229.

Velasco, G. (2016) The complex relationship of Tribbles pseudokinase 1, PML/RARA and C/EBPα in leukemia: two possible couples but not a trio. Haematologica. 101(10), 1129-1130.

Velasco, G., Sánchez, C., Guzmán, M. (2016) Anticancer mechanisms of cannabinoids. Curr. Oncol. 23(2),S23-32.

Velasco, G., Hernández-Tiedra, S., Dávila, D., Lorente, M. (2016) The use of cannabinoids as anticancer agents. Prog. Neuropsychopharmacol. Biol. Psychiatry. 64, 259-66.

Armstrong, J.L., Hill, D.S., McKee, C.S., Hernandez-Tiedra, S., Lorente, M., Lopez-Valero, I., Eleni Anagnostou, M., Babatunde, F., Corazzari, M., Redfern, C.P., Velasco, G.*, Lovat P*. (2015) Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death. J. Invest. Dermatol. 135(6), 1629-1637.

Cianfanelli, V., Fuoco, C., Lorente, M., Salazar, M., Quondamatteo, F., Gherardini, P.F, De Zio, D., Nazio, F., Antonioli, M., D’Orazio, M., Skobo, T., Bordi, M., Rohde, M., Dalla Valle, L., Helmer-Citterich, M., Gretzmeier, C., Dengje, l. J., Fimia, G.M., Piacentini, M., Di Bartolomeo, S., Velasco, G., Cecconi, F. (2015) AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation. Nature Cell Biology. (1), 20-30.

Salazar, M.*, Lorente, M.*, García-Taboada, E., Pérez-Gómez, E., Dávila, D., Zúñiga-García, P., María-Flores, J., Rodríguez, A., Hegedus, Z., Mosén-Ansorena, D., Aransay, A.M., Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J.L., Dusetti, N., Guzmán, M., Francis, S.E., Carracedo, A., Kiss-Toth, E., Velasco, G. (2015) Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation. Cell Death Differ. 22(1), 131-144.

Salazar, M., Lorente, M., Orea-Soufi, A., Dávila, D., Erazo, T., Lizcano, J., Carracedo, A., Kiss-Toth, E., Velasco, G. (2015) Oncosuppressive functions of tribbles pseudokinase 3. Biochem. Soc. Trans. 43(5), 1122-1126.

Hernán-Pérez de la Ossa, D.*, Lorente, M*., Gil-Alegre, M.E., Torres, S., García-Taboada, E., Aberturas, M del R., Molpeceres, J., Velasco, G.*, Torres-Suárez, A.I*. (2013) Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme. PLoS One. 8(1).

Salazar, M., Lorente, M., García-Taboada, E., Hernández-Tiedra, S., Davila, D., Francis, S.E., Guzmán, M., Kiss-Toth, E., Velasco, G. (2013) The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action. Biochim Biophys Acta. 1831 (10), 1573-8.