Publicaciones Recientes

Jefe de Grupo: Ismael Galve-Roperh

Campos A.C., Fogaça M.V., Scarante, F.F., Joca S.R., Salles AJ, Gomes F.V., Sonego A.B., Rodrigues N.S., Galve-Roperh, I., Guimarães F.S. (2017) Plastic mechanisms involved in the therapeutical effects of cannabidiol in psychiatric disorders. Frontiers in Pharmacology 8:269.

Bravo-Ferrer, I., Cuartero, MI., Zarruk, J.G., Pradillo, J.M., Hurtado, O., Romera, V.G., Díaz-Alonso, J., García-Segura, J.M., Guzmán, M., Lizasoain, I., Galve-Roperh, I., Moro M.A. (2017) Cannabinoid type 2 receptor drives neurogenesis and improves functional outcome after stroke. Stroke 48:204-212.

Díaz-Alonso, J.; de Salas-Quiroga, A., Garcez, P.P., Parsons, M., Andradas, C., Paraíso-Luna, J., García-Rincón, D., Sánchez, C., Guillemot, F., Guzmán, M., Galve-Roperh, I. (2017) Loss of cannabinoid CB1 receptors induces cortical migration malformations and increases seizure susceptibility. Cerebral Cortex  27:5303-5317.

Diaz-Alonso, J., Paraíso-Luna, J., Navarrete, C., del Rio, C., Cantarero, I., Palomares, B., Aguareles, J., Fernandez-Ruiz, J.J., Luz-Bellido, M., Pollastro, F., Appendino, G., Calzado, M.A., Galve-Roperh, I., Muñoz. E. (2016) VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease. Scientific Reports 19;6:29789.

de Salas-Quiroga, A., Díaz-Alonso, J., García-Rincón, D., Remmers, F., Vega, D., Gómez-Cañas, M., Lutz, B., Guzmán, M., Galve-Roperh, I. (2015) Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1 receptors on developing cortical neurons. Proc Natl Acad Sci USA 112:13693-8.

Stern, A.,J., C.,Gazarini, L., Vanvossen, A.C., Zuardi, W.A., Galve-Roperh, I., Guimaraes, F.S.,Takahashi, R.N., Bertoglio, L.J. (2015) Δ9-tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption. European Neuropsychopharmacology 25:958-65.

Díaz-Alonso, J., Aguado, T., de Salas-Quiroga, A., Ortega, Z., Guzmán, M., Galve-Roperh, I. (2014) CB1 Cannabinoid Receptor-Dependent Activation of mTORC1/Pax6 Signaling Drives Tbr2 Expression and Basal Progenitor Expansion in the Developing Mouse Cortex. Cereb Cortex. 25:2395-408.

Viar-Fogaça, M., Galve-Roperh, I., Guimarães, F.S. Campos, A.C. (2013) Cannabinoids, neurogenesis and antidepressants drugs: is there a link? Current Neuropharmacology 11:263-275.

Galve-Roperh, I., Chiurchiù, V., Díaz-Alonso, J., Bari, M., Guzman, M., Maccarrone, M. (2013) Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation. Progress Lipid Research 52:633-650.

Bishay, P., Häussler, A., Lim, H-Y., Oertel, B., Galve-Roperh, I., Ferreirós, N., Tegeder, I. (2013) Anandamide deficiency and heightened neuropathic pain in aged mice. Neuropharmacology 71:204-15.

Campos, A.C.,  Ortega, Z., Palazuelos, J., Fogaça, M.V., Aguiar, D.C., Diaz-Alonso, J., Ortega-Gutiérrez, S., Vázquez-Villa, H., Moreira, F.A., Guzmán, M, Guimarães, FS, Galve-Roperh, I. (2013) The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system. Int J Neuropsychopharmacology 9:1-13.

Díaz J, Aguado T., Wu C., Palazuelos, J., Hofmann, C., Garcez, P., Guillemot, F., Lu, H.C., Lutz, B., Guzmán, M., Galve-Roperh, I. (2012) CB1 cannabinoid receptors drive corticospinal motor neuron specification through the Ctip2/Satb2 transcriptional regulation axis. Journal of Neuroscience 32:16651-65.

Díaz-Alonso, J., Guzmán, M., Galve-Roperh, I. (2012) Endocannabinoids via CB1 receptors act as neurogenic niche cues during cortical development. Philosophical Transactions B 367, 3229-3241.

Palazuelos, J., Ortega, Z., Díaz-Alonso, J., Guzmán, M, Galve-Roperh, I. (2012) CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling. J. Biol Chem. 287:1198-209.